We’ve researched and tested dozens of natural probiotics — these are our top nine picks made with clean and organic ingredients for maximum benefit.
Probiotics are living organisms that are good for you (yes, they exist!) — think healthy bacteria, yeast, and spores. Once ingested, probiotic strains help restore your gut health, heighten immunity, reduce inflammation and allergies, and even support your mood.
Why should you look for natural and organic probiotics?
Natural and organic probiotics offer numerous benefits that conventional probiotics miss out on. They are free from harmful chemicals like pesticides, GMOs, and synthetics. Organic farming practices also contribute to a healthier soil ecosystem and higher quality ingredients that can be used in probiotic formulas to boost their benefits (think prebiotic fiber from organic fruits). Organic probiotics are also more sustainable, as less synthetics and better biodiversity in farming practices minimize adverse impacts on our environment.
As with any ingestible supplement, knowing what to look for in a healthy, effective probiotic is important. According to both the Cleveland Clinic and WebMD, you want to search for quality brand names. You’ll also want to look for a probiotic with one billion or more colony-forming units (CFUs) or active fluorescent units (AFUs), and check that it aligns with your preferred dosage and form (consider capsules, gummies, or powder).
We’ve found nine of the best and most trusted natural probiotics out there, ranging from USDA certified organic formulas for immunity, to vegan options for gut health and digestion, to natural capsules for pregnancy or vaginal health. We also recommend chatting with your doctor for personalized suggestions or before starting any new supplement. If you have a probiotic you already love, we’d love to hear in the comments below!
Our criteria:
- NATURAL, HIGH-QUALITY INGREDIENTS | Each of these probiotics is made from natural ingredients that are third-party tested and highly effective.
- AFFORDABILITY | We’ve offered a variety of choices for probiotics at various price points, prioritizing budget-friendly options.
- ACTIVE FLUORESCENT UNITS (AFU) | Each of these brands provides detailed information on their CFU/AFU count, ensuring plenty of gut-friendly microorganisms are reaching your colon, where they’ll go to work!
For more supplement and vitamin options, check out our guides to the best multivitamins and probiotics for women. For parents-to-be, we also recommend looking at our prenatal vitamins roundup!
**This review is not health advice. Please talk to your OBGYN or healthcare provider before adding any supplements to your diet.
Best Overall | Best Powdered Probiotic | Most Affordable
1. Seed
Best For | Monthly subscription
Natural & Organic Ingredients | Vegan; free from gluten, dairy, soy, nut, shellfish, corn, and sesame; glyphosate/AMPA-free, no binders or preservatives; prop-65 compliant
Price | $50/month
Seed DS-01™ Daily Synbiotic is a science-backed probiotic with 24 clinically studied strains to support whole-body health beyond just your gut. Engineered to survive acid, enzymes, moisture, and heat, these vegan probiotics improve skin, heart, and gut health all at once. The formula has also been tested for 400+ allergens and pesticide residues to ensure that everyone can give it a try. Orders start at $50/month; skip or cancel at any time, and enjoy a 30-day risk-free guarantee.
2. Perelel
Best For | Pregnancy and breastfeeding
Natural & Organic Ingredients | Clinically-backed ingredients; gluten-, dairy- & soy-free; no colorants or synthetic fillers; non-GMO
Price | $27/month; discounted subscriptions available (15% off)
For those of us looking for immunity, gut, and vaginal health support with a supplement that is safe for pregnancy and breastfeeding, look no further than Perelel. The brand’s daily probiotic contains 10 billion CFUs that can be taken daily. And whether you’re trying to conceive, already pregnant, or postpartum, this third-party tested formula is designed specifically for you (in a thoughtful, no-nausea formula!). The diverse bacterial strains support your GI tract and vaginal flora, and also build your baby’s microbiome throughout pregnancy.
Perelel Review | “I absolutely love and highly recommend this probiotic! I only wish I had started taking it earlier in my pregnancy. I used to struggle with constipation with my old probiotic and a daily stool softener. I no longer have to take the stool softener with Perelel’s probiotic.” – Rebecca G. [See all reviews]
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3. AG1 (Athletic Greens)
Best For | Comprehensive nutrition on the go
Natural & Organic Ingredients | Vegan; organic ingredients; non-GMO; free of fillers & preservatives; free from gluten, corn, eggs, peanuts, dairy, and animal by-products
Price | $99/month; discounted subscriptions available (20%+ off)
AG1 (formerly Athletic Greens) is a drinkable, portable powder supplement that covers all your daily nutrition needs through a mix of greens, vitamins, nutrients, and pre- and probiotics. Just one scoop of this sugar-free pineapple and vanilla-flavored powder adds 75 superpower nutrients to your diet. (Read our review on whether AG1 covered all our nutrition needs.) The formula includes antioxidants, herbs, enzymes, and multi minerals to name a few. All this is in addition to 7.2 billion CFU! AG1 is a great choice for those who prefer supplementing via powder or have difficulty swallowing pills. Take their shelf-stable travel packs on the go with you, so you never miss a day!
Our Editor’s Review | “Does AG1 taste good, and does it make you feel better? The short answer is yes to both. I’m always skeptical when trying new health products […] but AG1 tastes wonderful. I prefer drinking it as prescribed, mixed in with 8 ounces of cold water. But I’ve also mixed it into smoothies.” – Kayti Christian, Contributing Editor [Read our full review.]
4. Ritual
Best For | Multivitamin supplement with probiotics
Natural & Organic Ingredients | Vegan; gluten-free and major allergen-friendly; non-GMO; third-party tested; traceable ingredients
Price | $54/month; subscriptions available
Ritual‘s probiotic formula is like no other. This Synbiotic+ is made with 3-in-1 clinically-studied prebiotics, probiotics, and postbiotics to not only support your gut, but build your overall foundational health. (70% of our immune system is in the gut!). Each capsule contains 11 billion CFUs, plus two of the world’s most clinically studied probiotic strains. Ritual is Made Traceable® so you know exactly where each ingredient in the formula comes from, and what you’re putting in your body. It’s also shelf-stable and is formulated with a delayed-release capsule so it reaches your colon while still alive. Up your gut health game with this well-rounded supplement!
Ritual Review | “Love this product. It does not stress your digestive system...[and] works gently. It took about 30 days for my system to adjust. I experienced mild queasiness periodically. Which lasted about 10 – 15 minutes. I didn’t experience any bloating or flatulence. I like that it includes a prebiotic, probiotic, and a prebiotic. Overall, I am very happy with Synbiotic, and will continue to use it.” – Valerie O. [See all reviews]
5. Thorne
Best For | Vaginal health & hormone support
Natural & Organic Ingredients | Gluten-free, dairy-free, soy-free
Price | $30–$49/month; discounted subscriptions available (20% off)
Thorne’s collection of daily probiotics is made with clinically studied strains and proprietary blends for targeted support. Their FloraMend Prime Probiotic® works to balance the gut flora to help support a stronger immune system and healthy neurotransmitter production, while their Women’s Daily Probiotic supports those with urinary and vaginal issues. Their EnteroMend® product also helps maintain a healthy intestinal tract through a unique botanical, probiotic, and amino acid blend. No matter what your needs are, Thorne has a supplement for you. It’s no wonder Thorne is known for being the #1 most highly recommended brand by Healthcare practitioners!
Thorne Review | “I took this to Mexico with me where my tummy typically takes a turn for the worst, and these were a game changer! It didn’t matter what I ate there, these kept me regular the whole time and made the trip better than normal considering I didn’t have to worry about it.” – Juli C. [See all reviews]
6. The Nue Co.
Best For | IBS support
Natural & Organic Ingredients | Vegan; non-GMO; organic inulin; traceable ingredients
Price | $55/month; discounted subscriptions available (40% off)
The Nue Co.’s Prebiotic + Probiotic is like a one-two punch for gut health — in a good way! Each dose (two capsules) contains 15 billion spores that get right to work once they reach your small intestine. Within weeks, you can expect relief from a number of digestive issues, including abdominal pain, gas, constipation, bloating, and IBS. We also like that this certified B Corp uses sustainable practices in their production, including packaging in an infinitely recyclable amber glass jar and offering refills.
The Nue Co. Review | “After extensive antibiotic use, I suffered from terrible digestion issues, stomach aches, and insane bloating. Within 12 days of using these, my bloating has shrunk an inch and I have half of the stomach aches I normally have after eating. One jar came shattered and Alex from customer service immediately sent out a replacement. Highly recommend this company and this product.” – Samantha N. [See all reviews]
7. MaryRuth Organics
Best For | Multi-benefits
Natural & Organic Ingredients | Vegan; gluten-, dairy- & soy-free; USDA organic options available; non-GMO
Price | $30/month; discounted subscriptions available (10% off)
MaryRuth Organics has you covered with their wide selection of probiotics supplements that not only nourish your gut health, but provide whole body support. Whether you’re looking to improve your hair, skin, and nails, or benefit from anti-inflammatory support, we love that these vegan probiotic supplements offer added ingredients like turmeric, biotin, and phytoceramides, helping us benefit from more while consuming less! MaryRuth formulas come in gummy, liquid, and capsule form, and include options for infants and kids so the entire family can reap the benefits!
MaryRuth Organics Review | “As we age things start happening to us that are mostly out of our control. I started having very brittle nails, my hair looked old, and my skin had become dry. In my quest to help myself look and feel better I came across MaryRuth’s products. One of which is Probiotic Beauty+, this product has helped with all my issues, I have seen an improvement in all these areas and this has made me feel so much better about myself. The fact that it has probiotics is an added plus, not only does this product help you look better on the outside it helps on the inside as well. Can’t say enough about this product, my self esteem and my want to live a healthier lifestyle.” – Eveline P. [See all reviews]
8. Garden of Life
Best For | High CFU count
Natural & Organic Ingredients | No binders, fillers or carriers; whole food vitamins; non-GMO; dairy-free & soy-free options available
Price | $34–$48/month; discounted subscriptions available (15%+ off & free shipping)
Certified B Corp Garden of Life is all about helping you perform your best with its holistic supplements, powders, and effective probiotics. All products are USDA certified organic, and you can choose from dozens of options to find the best fit for you, from the once-daily women’s probiotic to cherry chewables for kids to prenatal capsules. Find Garden of Life online at marketplaces like Thrive, directly via the brand, or in stores.
Garden of Life Review | “My wife suffered from c. diff. colitis for decades before medical science developed an effective treatment (FMT). Her physician and staff researched the best product to maintain the gains from the transplant and chose this product. This product has kept her free from c. diff. problems for several years and is now a daily staple.” – Jack H. [See all reviews]
9. Ora
Best For | Powder supplement
Natural & Organic Ingredients | Dairy-free, gluten-free, soy-free; non-GMO; organic; vegan
Price | $41/month; discounted subscriptions available (20% off)
Ora’s Trust Your Gut is a great powder alternative if you’re not a fan of capsules. This formula includes 20 billion probiotics, prebiotics, studied strains, and a flavor of your choice: apple raspberry or lavender lemonade. It’s certified organic, vegan, and shelf-stable too, so it’s easy to include in meals or take while traveling. Choose from 30 to 90 days servings or a discounted subscription and see why it has over 900 glowing reviews!
Ora Review | “This is a great product to have if you have stomach issues or bowel movement difficulties. I have been using this for over 5 months and has helped my body in many ways as I have issues going to the bathroom and have constipation. I also have gluten sensitivities and it is very easy on the stomach. [I’ve]used this for my postpartum and it has helped and is helping my body to function normally again. The bonus part is it tastes really good!” – Cynthia B. [See all reviews]
Featured image from Seed
